What occurs during the proliferation phase of wound healing?

• A. Contraction and tissue granulation
• B. Infection and inflammation
• C. Scab formation and vascularization
• D. Dermal remodeling and scar formation

Answer: (A)

During the proliferation phase of wound healing, the primary processes include contraction and the formation of granulation tissue. This phase follows the inflammatory response and is characterized by the regeneration of skin and tissue. Granulation tissue is the new connective tissue that forms over the wound, providing a framework for further healing. This tissue is typically rich in collagen and has a high density of blood vessels, which are necessary for delivering nutrients and oxygen to aid the healing process.

Contraction refers to the process where the edges of the wound start to pull together, reducing its size. This is facilitated by myofibroblasts, which are specialized cells that help in this contraction. Overall, the proliferation phase is crucial because it lays down the foundation for new tissue, allowing for eventual closure of the wound.

The other options may encompass processes that occur outside of the proliferation phase, such as inflammation, which is primarily a part of the initial response to injury, or remodeling, which occurs later after the proliferation phase. Each stage of wound healing has its distinct characteristics and timeframes, making it essential to recognize the specific events that define the proliferation phase.